In the fast-paced world of life sciences, innovation requires more than just bright ideas – it takes trust, commitment, and strong partnerships. Through this, we successfully developed a state-of-the-art instrument for automated clean-up and size selection of nucleic acids – together with our partner Hamilton.
From idea to early functional model
The idea for the Microlab PuriFY was sparked in 2017 at HSE. The vision was to develop a revolutionary automated tool that streamlines labor-intensive nucleic acid purification and size selection. The pioneering idea led to the development of a functional model demonstrating not just feasibility but real promise.
Strategic partnership begins
By 2022, this vision evolved into a full-scale development project in partnership with Hamilton. Under a clearly defined collaboration model, we took the lead on the instrument development – including mechatronic, software, firmware, and consumable design – while Hamilton spearheaded the injection molding, applications, production, and market introduction. This division of responsibilities created an agile and focused team dynamic, where both partners could leverage their core strengths.
From concept to reality in record time
Development officially kicked off in January 2023, with an ambitious target: to present the solution at the SLAS 2025 in San Diego. Despite challenging timelines, the joint team delivered — right on schedule.
Key milestones included:
- Three iterative development loops to refine functionality and performance including build of two prototype versions
- Design transfer to Hamilton by summer 2024 for pilot instrument production
- System verification, safety certification, and EMC compliance completed well ahead of schedule
- First instrument availability confirmed for May 2025
Overcoming challenges together
Every innovation journey comes with hurdles – and this one was no exception. From unexpected production issues to edge-case reliability concerns, the team faced – and solved – complex challenges together. This was only possible through strong leadership and technical excellence across innovation, system engineering, and molecular biology.
As an example, the highly-accurate small-volume dispensing over a wide range of environmental parameters (temperature, humidity, pressure) is only achievable thanks to a well-designed system in combination with a sophisticated model-based algorithm.
By replacing tip-based pipetting with a patented consumable (featuring a micro-pore of 200 µm diameter) and implementing a multichannel manifold using pressure over liquid technology (MagPore Technology), plastic waste as well as hands-on time are reduced by 80%.
Looking ahead
This launch proves the power of two companies aligning their goals and talents. At HSE, we deeply value the trusting and collaborative interaction with Hamilton that made this success possible.
As we look to the future, we’re eager to know what the next project will bring. Together, we’ve proven that strong partnerships don’t just deliver on time – they deliver innovation and excellence.
Read our case study to learn more about the project's highlights, challenges and innovative solution!
Discover more about the Hamilton Microlab PuriFY.